Overview
Senior Clinical Data Manager Jobs in City of Johannesburg, Gauteng, South Africa at ICON Strategic Solutions
Title: Senior Clinical Data Manager
Company: ICON Strategic Solutions
Location: City of Johannesburg, Gauteng, South Africa
Senior Clinical Data Manager (Senior Clinical Data Science Lead)
Poland, UK, South Africa- Remote
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
As a Senior Clinical Data Manager at ICON, you will be client dedicated, serving as the primary data lead across global clinical trials and partnering closely with sponsors to drive high-quality, regulatory-compliant data delivery from study start-up through database lock.
Key responsibilities
- Acting as the primary data lead within cross-functional study teams and sponsor partnerships
- Driving study start-up activities including EDC build, system integrations, UAT, and key data management deliverables
- Overseeing data review, reconciliation, vendor management, and database lock activities
- Ensuring compliance with CDISC standards, ICH-GCP requirements, and regulatory expectations
- Identifying and mitigating risks while driving continuous improvement and operational excellence
You will Have/Be:
- Bachelor’s degree in Life Sciences, Health Sciences, or a related discipline
- 6+ years of Clinical Data Management or Clinical Data Science experience within a CRO or pharmaceutical environment
- Proven experience leading studies across the full clinical trial lifecycle
- Experience as a primary Data Lead on complex studies and/or extensive hands-on data review and reconciliation experience across EDC, vendor, eCOA, IRT, and SAE data
- Strong vendor oversight and stakeholder management experience
- Hands-on experience with EDC systems, with Veeva EDC preferred
- Knowledge of CDISC standards, including SDTM
- Strong understanding of clinical trial processes, regulatory requirements, and ICH-GCP
- Excellent communication, problem-solving, and project leadership skills
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